CDC Website: Year 2000 Studies Prove Anti-Bacteria Soaps Do Not Kill Deadly E-Coli/ MRSA BACTERIA

... We examined this question by testing triclosan activity in a commercial soap. To achieve a 90% death rate, wild-type E. coli required exposure to 150 µg/mL of triclosan in soap for 2 hours at 37ºC. Two to four times that amount was required by the mutant strain. ... (Use alcohol based hand sanitizer in the kitchen after scrubbing with regular soap and water. Jim)

We have become a society where Profits Trumps All Human Needs Including Health of Our Loved Ones.

Deadly E-Coli 0157-H7 is present in all commonly used facilities and even in half our kitchens in our homes due to the introduction of factory farming and antibacterial soap. Even now, the soap companies such as Proctor & Gamble and the news media refuse to discuss this problem honestly. This long report should be read so I provided a link. A solution of half vinegar and water in a spray bottle will probably kill the bacterial. The sale of Clorox wipes has mushroomed.

Deadly 0157-H7 e-coli is present in half the kitchens in the USA from corporate hamburgers from all parts of world mixed together from scraps on the floor and the body of the cows exposed to fecal matter from cows which stand in their own shit while feeding. Even one bacteria can grow enough and doubles every four hours. Burn your hamburgers or just don't buy commercial hamburgers or eat one at a restaurant or Fast Food Joint. Even having meat ground fresh for you is not full-proof, but likely safer than buying the commercial hamburger.

Your kitchen can be kept e-coli free by never using the same cutting board for meat or chicken. I tend to avoid deli meats except at a store I trust, but only occasionally. Listeria in Wisconsin killed 100 people from contaminated hotdogs and other deli meats by Sara Lee foods. The executives who knew about the problem but did nothing were given a fine, but not put in jail. Listeria is more toxic than 0157-H7 e-coli.

Today Dr Oz http://doctoroz.com on ABC 3 PM ET/PT talked about microbes hazardous to our health. One woman on the show got MRSA while being treated for breast cancer. She has not been able to get rid of the MRSA and got it twice and still has a small amount of MRSA in her body only to grow again when her immunity is down. He has videos for each section. I would recommend everyone to record and/or watch this show daily. I watch while jogging on my rebounder/mini trampoline for about one hour.

Jim Kawakami, Nov 10, 2009, http://jimboguy.blogspot.com

CDC Website: Year 2000 Studies Prove Anti-Bacteria Soaps Do Not Kill Deadly 0157-H7 e-coli BACTERIA

... We examined this question by testing triclosan activity in a commercial soap. To achieve a 90% death rate, wild-type E. coli required exposure to 150 µg/mL of triclosan in soap for 2 hours at 37ºC. Two to four times that amount was required by the mutant. ...

Presentation from the 2000 Emerging Infectious Diseases Conference in Atlanta, Georgia Antibacterial Household Products: Cause for Concern Stuart B. Levy Tufts University School of Medicine, Boston, Massachusetts, USA The recent entry of products containing antibacterial agents into healthy households has escalated from a few dozen products in the mid-1990s to more than 700 today. Antibacterial products were developed and have been successfully used to prevent transmission of disease-causing microorganisms among patients, particularly in hospitals. They are now being added to products used in healthy households, even though an added health benefit has not been demonstrated. Scientists are concerned that the antibacterial agents will select bacteria resistant to them and cross-resistant to antibiotics. Moreover, if they alter a person's microflora, they may negatively affect the normal maturation of the T helper cell response of the immune system to commensal flora antigens; this change could lead to a greater chance of allergies in children. As with antibiotics, prudent use of these products is urged. Their designated purpose is to protect vulnerable patients. Antibiotics are critical to the treatment of bacterial infections. However, after years of overuse and misuse of these drugs, bacteria have developed antibiotic resistance, which has become a global health crisis (1, 2). The relatively recent increase of surface antibacterial agents or biocides into healthy households may contribute to the resistance problem. The antibacterial substances added to diverse household cleaning products are similar to antibiotics in many ways. When used correctly, they inhibit bacterial growth. However, their purpose is not to cure disease but to prevent transmission of disease-causing microorganisms to noninfected persons. Like antibiotics, these products can select resistant strains and, therefore, overuse in the home can be expected to propagate resistant microbial variants (3-6). Moreover, these agents, like antibiotics, are not cure-alls but have a designated purpose. Whereas antibiotics are designed to treat bacterial (not viral) infections, antibacterial products protect vulnerable patients from infectious disease-causing organisms. Neither are demonstrably useful in the healthy household. Proliferation of Antibacterial Products Seven years ago, only a few dozen products containing antibacterial agents were being marketed for the home. Now more than 700 are available. The public is being bombarded with ads for cleansers, soaps, toothbrushes, dishwashing detergents, and hand lotions, all containing antibacterial agents. Likewise, we hear about "superbugs" and deadly viruses. Germs have become the buzzword for a danger people want to eliminate from their surroundings. In response to these messages, people are buying antibacterial products because they think these products offer health protection for them and their families. Among the newer products in the antibacterial craze are antibacterial window cleaner and antibacterial chopsticks. Antibacterial agents are now in plastic food storage containers in England. In Italy, antibacterial products are touted in public laundries. In the Boston area, you can purchase a mattress completely impregnated with an antibacterial agent. Whole bathrooms and bedrooms can be outfitted with products containing triclosan (a common antibacterial agent), including pillows, sheets, towels, and slippers. Development of Resistance Bacteria are not about to succumb to this deluge, however. Through mutation, some of their progeny emerge with resistance to the antibacterial agent aimed at it, and possibly to other antimicrobial agents as well (4). Laboratory-derived mutants of Pseudomonas stutzeri with resistance to the cationic biocide chlorhexidine were also cross-resistant to antibiotics (nalidixic acid, erythromycin, and ampicillin) (7). In a recent study, 7% ofListeria monocytogenes strains isolated from the environment and food products showed resistance to quaternary ammonium compounds (8). Laura McMurry in my laboratory group conducted experiments to determine whether triclosan had a particular cellular site for its antibacterial activity. She used a classic genetic technique, the isolation of resistant mutants of Escherichia coli, to identify its possible target. Surprisingly, finding the cellular site proved easy. In fact, mutants appeared with low, medium, and high-level resistance (3). They all had a mutation in one gene, the fabI gene (3) (Table 1). This finding indicated that triclosan had a target for the enoyl reductase essential in fatty acid biosynthesis. In the presence of triclosan or a know fabI inhibitor (diazoborine) fatty acid biosynthesis was inhibited, whereas the antibiotics chloramphenicol or ciprofloxacin with other targets had little effect on fatty acid biosynthesis (Table 2). In comparison with the wild-type E. coli, the mutant required up to 100 times more triclosan to show even minimal inhibition of fatty acid biosynthesis (3).

		Table 1. Selection of Escherichia coli with triclosan resistance (3) MIC Change Mutated E. coli (µg/ml) (fold) gene AG100 0.05 1.0 —— AG100-1 0.20 4.0 fabI (F203L) AG100-2 1.90 40.0 fabI (M159T) AG100-3 25.00 500.0 fabI (G93V)
		Table 2. Effect of various drugs on fatty acid/lipid synthesis in intact cells Strain Drug µg/ml % inhibition AG100 Triclosan 0.24 92 (wild-type) Diazaborine 8.00 93 Chloramphenicol 13.00 19 Ciprofloxacin 0.045 2 AGT11 Triclosan 0.24 2 (G93V) Triclosan 1.40 7 Triclosan 8.60 37 Triclosan 25.90 75
		One might argue that the high concentration of triclosan usually found in soap, e.g. 2,500 µg/ml, is enough to kill even resistant strains. We examined this question by testing triclosan activity in a commercial soap. To achieve a 90% death rate, wild-type E. coli required exposure to 150 µg/mL of triclosan in soap for 2 hours at 37ºC. Two to four times that amount was required by the mutant. By itself, triclosan was more active, killing E. coli at 6 µg/ml, and there was an even greater difference between the amounts required to kill wild-type and mutant E. coli. The soap seemed to decrease triclosan's effectiveness (Table 3). The mutant E. coli strains are truly resistant and would survive in triclosan-treated soaps diluted with as little as 3 parts water. Most importantly, the time, temperature, and amount needed to kill the bacteria greatly exceeded the average 5-second hand washing performed by most people. ... http://www.cdc.gov/ncidod/eid/vol7no3_supp/levy.htm