Wednesday, October 27, 2010

Cancer Radiation Risk Adults Earlier Gene Mutations Promotion Pre-Cancer Cells

Tags: Cancer Radiation Risk Adults Earlier Gene Mutations Promotion Pre-Cancer Cells

ScienceDaily (Oct. 27, 2010) — http://www.sciencedaily.com/releases/2010/10/101025161028.htm


... The researchers developed a model based on these biological effects and applied the model to the Japanese atomic bomb survivor data. They found that the model was able to reproduce the cancer risk patterns associated with age at radiation exposure observed in these survivors. They then applied the same model to predict cancer risks as a function of age in the U.S. population and found that the cancer risks predicted by the model were consistent with the data in the age range from about 30 to 60.

The authors conclude that cancer risk after exposure in middle age may increase for some tumor types contrary to conventional wisdom. They add that these findings could have practical implications regarding x-ray diagnostic tests, which are predominantly performed on middle aged adults, as well as for occupations that involve radiation exposures, again where most exposures are in middle age.

"Overall, the weight of the epidemiological evidence suggests that for adult exposures, radiation risks do not generally decrease with increasing age at exposure," they write, "and the mechanistic underpinning described here provides this conclusion with some biological plausibility." ...

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