Thursday, April 29, 2010

Lower Fructose Maintains Healthy Weight, Lowers BP, Uric Acid, High Blood Glucose, Diabetes, and Aging

Tags: Aging from Fructose, proteins, and amino acids AGEs, Sugar Fix, Gatorade, Major Diseases Caused

Fructose and glucose react with proteins and amino acids to produce advanced glycation or glycosylation via a cross-linking process which has the appropriate acronym of AGEs. Since I read the Scientific American article more than three decades ago, I had been fairly careful in keeping my sugar intake low. But the hidden HFCS in Fast Foods fooled me. Obama has come to the rescue by putting in the Healthcare Bill, a provision for Fast Food and restaurants to list all ingredients and calories on foods they sell. (See Chapter 7, "The Sugar Fix: The High Fructose Fallout That is Making You Fat and Sick" by Richard J. Johnson, MD with Timothy Gower, 2008

Again the Republicans under Reagan made corn very cheap with huge subsidies, tariffs on cane sugar, and blessed Corn Syrup or High Fructose Corn Sugar or HFCS as safe without any testing on animals and humans. But it may have passed the FDA anyway because the effects are chronic and not sanctioned for regulation. The FDA spoke out against Tobacco, but could not ban it. But a knowledge campaign proved quite effective. The same needs to be done for HFCS which is extremely dangerous for our health. It is already starting to work with the soft drink companies removing it "voluntarily from schools and Pepsi's Gatorade in the process of removing HFCS. Sugar, The Bitter Truth
Jim Kawakami, April 29, 2010,
Wikipedia: ... AGEs, contributes to age- and diabetes-related chronic inflammatory diseases such as atherosclerosis, asthma, arthritis, myocardial infarction, nephropathy, retinopathy, or neuropathy. There may be some chemicals, such as aminoguanidine, that limit the formation of AGEs.[16] ... AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases[19][20][21]. They are also believed to play a causative role in the vascular complications of diabetes mellitus.[22] They have a range of pathological effects, including increasing vascular permeability, inhibition of vascular dilation by interfering with nitric oxide, oxidising LDL,[23] binding cells including macrophage, endothelial and mesangial cells to induce the secretion of a variety of cytokines and enhancing oxidative stress[23][24] ...
Hilary Parker, Princeton University Website March 22, 2010, ... High-fructose corn syrup and sucrose are both compounds that contain the simple sugars fructose and glucose, but there at least two clear differences between them. First, sucrose is composed of equal amounts of the two simple sugars -- it is 50 percent fructose and 50 percent glucose -- but the typical high-fructose corn syrup used in this study features a slightly imbalanced ratio, containing 55 percent fructose and 42 percent glucose. Larger sugar molecules called higher saccharides make up the remaining 3 percent of the sweetener.
Second, as a result of the manufacturing process for high-fructose corn syrup, the fructose molecules in the sweetener are free and unbound, ready for absorption and utilization. In contrast, every fructose molecule in sucrose that comes from cane sugar or beet sugar is bound to a corresponding glucose molecule and must go through an extra metabolic step before it can be utilized.
This creates a fascinating puzzle. The rats in the Princeton study became obese by drinking high-fructose corn syrup, but not by drinking sucrose. The critical differences in appetite, metabolism and gene expression that underlie this phenomenon are yet to be discovered, but may relate to the fact that excess fructose is being metabolized to produce fat, while glucose is largely being processed for energy or stored as a carbohydrate, called glycogen, in the liver and muscles.
In the 40 years since the introduction of high-fructose corn syrup as a cost-effective sweetener in the American diet, rates of obesity in the U.S. have skyrocketed, according to the Centers for Disease Control and Prevention. In 1970, around 15 percent of the U.S. population met the definition for obesity; today, roughly one-third of the American adults are considered obese, the CDC reported. High-fructose corn syrup is found in a wide range of foods and beverages, including fruit juice, soda, cereal, bread, yogurt, ketchup and mayonnaise. On average, Americans consume 60 pounds of the sweetener per person every year. ...

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