A sweet problem: Princeton researchers find that high-fructose corn syrup prompts considerably more weight gain
by Hilary Parker, March 22, 2010, http://www.princeton.edu/main/news/archive/S26/91/22K07/
A Princeton University research team has demonstrated that all sweeteners are not equal when it comes to weight gain: Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.
In addition to causing significant weight gain in lab animals, long-term consumption of high-fructose corn syrup also led to abnormal increases in body fat, especially in the abdomen, and a rise in circulating blood fats called triglycerides. The researchers say the work sheds light on the factors contributing to obesity trends in the United States.
"Some people have claimed that high-fructose corn syrup is no different than other sweeteners when it comes to weight gain and obesity, but our results make it clear that this just isn't true, at least under the conditions of our tests," said psychology professor Bart Hoebel, who specializes in the neuroscience of appetite, weight and sugar addiction. "When rats are drinking high-fructose corn syrup at levels well below those in soda pop, they're becoming obese -- every single one, across the board. Even when rats are fed a high-fat diet, you don't see this; they don't all gain extra weight." http://www.princeton.edu/main/news/archive/S26/91/22K07/
Richard Johnson, MD, also reported in the same peer reviewed journals that the metabolism of fructose in our cells uses up ATP,
Wikipedia: … Metabolic processes that use ATP as an energy source convert it back into its precursors. ATP is therefore continuously recycled in organisms: the human body, which on average contains 250 grams (8.8 oz) of ATP turns over its own weight in ATP each day. …
The structure of this molecule consists of a purine base (adenine) attached to the 1' carbon atom of a pentose sugar (ribose). ... When ATP is used in DNA synthesis, the ribose sugar is first converted to deoxyribose by ribonucleotide reductase. … http://en.wikipedia.org/wiki/Adenosine_triphosphate
which turns into purine on cell death and the purine is converted to Uric Acid. Recent publications has proved that uric acid inflames the blood vessels which prevents expansion of the blood vessel so blood pressure increases to get enough blood through the vessels. The higher blood pressure in kidneys increases even more much so that kidneys function goes down. It was reported a few weeks ago in the online Nephrology publication. Also when kidney patients are treated to reduce uric acid, kidney deterioration slows down considerably.
jim kawakami, July 02, 2010, http://jimboguy.blogspot.com
Study: High-Fructose Diets May Raise Blood Pressure
Added Sugar May Be Linked to Hypertension Risk
By Denise Mann
WebMD Health News
Reviewed by Louise Chang, MD
July 1, 2010 -- Foods and beverages with high amounts of fructose from added sugar may increase your risk of developing high blood pressure, according to a new study in the Journal of the American Society of Nephrology. High blood pressure is a major risk factor for heart attack and stroke.
A type of sugar, fructose is a key ingredient in table sugar and high-fructose corn syrup. Added sugars are found in processed foods such as candy, cookies, and cakes, as well as soda.
For the study, data on 4,528 U.S. adults were collected from the National Health and Nutrition Examination Survey in 2003-2006. Fructose intake was calculated based on self-reported diet information. Those participants who reported eating or drinking 74 grams of fructose or more per day (which the study equates to 2.5 sugary soft drinks per day) had a higher risk of high blood pressure than their counterparts who got less fructose. The findings took into account factors such as age, smoking history, physical activity level, and salt and alcohol intake.
However, the study doesn’t prove that fructose was the cause for the rise in risk.
A link between added sugars and blood pressure is controversial. There are several theories about how fructose affects blood pressure levels, but none is firmly established. For example, high-fructose corn syrup may raise uric acid levels, which have been linked to high blood pressure.
“Limiting fructose intake is readily feasible, and in light of our results, prospective studies are needed to assess whether decreased intake of fructose from added sugars will reduce the incidence of hypertension and the burden of cardiovascular disease in the U.S. adult population,” conclude researchers who were led by Diana I. Jalal, MD, of the University of Colorado Denver Health Sciences Center in Denver.
Study Flawed, Critics Say
Not so fast, according to The Corn Refiners Association, a national trade group based in Washington, D.C., and others.
The Corn Refiners Association takes issues with the findings and the methodology used in the new study. “The authors failed to learn the true composition of sweeteners used in caloric soft drinks,” according to a statement released by the group. “Caloric soft drinks are not sweetened with 100% fructose. The sweeteners they contain are comprised of almost equal portions of the two simple sugars fructose and glucose, because they are sweetened with either sucrose (table sugar) or high fructose corn syrup (corn sugar).” … http://www.webmd.com/hypertension-high-blood-pressure/news/20100701/study-high-fructose-diets-may-raise-blood-pressure