In chapter 3 of Michael F. Holick’s book The Vitamin D Solution, 2010, he discusses how the bone remodelling medications of bisphosphonates such as Fosamax, Boniva, Miacalcin, Evista, Forteo (not bisphosphonate which increases parathyroid hormone generation which does activate 25 hydroxy vitamin D), and Reclast, a once a year bisphosphonate 15-minute injectable drug.
Dr. Holick points out that the fracture that is the most serious for fatalities is hip fracture so Fosamax, Actonel, and Reclast seem to be the one to take. If you have reflux disease which Holick does not mention, my guess is that Reclast (Zoledronic acid injectable solution) might be the most effective doesn’t have the drawback of irritating our esophagus.
Vitamin D is necessary to carry the calcium from the small intestines into the blood stream.
When people have Osteomalacia or soft bones experience bone pain because the bone expands to irritate the nerve fibers which is diagnosed as Fibromyalgia. You can tell if you press down the outside of the shin bone or breast bone. A gentle press causes pain.
The treatment for low vitamin D is often giving 50,000 IU of vitamin D3 by prescription each week for two or three months and checking the non-active metabolite 25-hydroxy-vitamin D in your blood. Check to see the cost of this test. Some charge much too much and see if it is covered. Dr. Holick talks about people taking 1,000 IU up to 5,000 IU daily. I found that 5,000 IU of vitamin D3 daily works best for me putting me at a stable level of over 50 nanograms/ml. About 3,000 IU or 60% is absorbed. Obese patients require twice the dose.
Jim Kawakami, Nov 19, 2010, http://jimboguy.blogspot.com